Canada's program of historical commemoration recognizes nationally significant places, persons and events of Canadian history. Designations of national historic significance are made by the Minister of the Environment on the advice of the Historic Sites and Monuments Board of Canada.
- Alcock - Brown Transatlantic Flight, St. John's, Newfoundland
- American Military Presence in Newfoundland, Argentia, Newfoundland
- Atlantic Charter, Placentia - Ship Harbour, Newfoundland
- Bartlett, Captain Robert Abram, Brigus, Newfoundland
- Basilica of St. John the Baptist, St. John's, Newfoundland
- Basque Whaling in Labrador, Red Bay, Newfoundland
- Battle Harbour Historic District, Battle Harbour, Labrador
- Battle of Signal Hill, St. John's, Newfoundland
- Bennett, Charles Fox, St. John's, Newfoundland
- Beothuks, Grand Falls, Newfoundland
- Bond, Sir Robert, Whitbourne, Newfoundland
- Boyd's Cove Beothuk, Boyd's Cove, Newfoundland
- Cable Building, Bay Roberts, Newfoundland
- Cabot's Landfall in the New World, Cape Bonavista, Newfoundland
- Canadian Military Presence in Newfoundland, Botwood, Newfoundland
- Cape Pine Lighthouse, Cape Pine, Newfoundland
- Cape Race Lighthouse, Cape Race, Newfoundland
- Cape Spear, Cape Spear, Newfoundland
- Carbonear Island, Carbonear, Newfoundland
- Carson, William, St. John's, Newfoundland
- Carter, Sir Frederick Bowker Terrington, St. John's, Newfoundland
- Castle Hill, Placentia, Newfoundland
- Christ Church / Quidi Vidi Church, St. John's, Newfoundland
- Clinch, Reverend John, Trinity, Newfoundland
- Coaker, Sir William Ford, Port Union, Newfoundland
- Colony of Avalon, Ferryland, Newfoundland
- Cook, Captain James, Corner Brook, Newfoundland
- Cormack, William Epps, Milton, Newfoundland
- Coughlan, Reverend Laurence, Harbour Grace, Newfoundland
- Cullen, Maurice Galbraith, St. John's, Newfoundland
- Demasduit, Botwood, Newfoundland
- Duley, Margaret Iris, St. John's, Newfoundland
- Feild, Bishop Edward, St. John's, Newfoundland
- Fishing Industry on the East Coast, Bonavista, Newfoundland
- Fleming, Bishop Michael Anthony, St. John's, Newfoundland
- Fleur de Lys Soapstone Quarries, Baie Verte, Newfoundland
- Former Bank of British North America, St. John's, Newfoundland
- Former Carbonear Railway Station (Newfoundland Railway), Carbonear, Newfoundland
- Former Newfoundland Railway Headquarters, St. John's, Newfoundland
- Fort Amherst, St. John's, Newfoundland
- Fort Townshend, St. John's, Newfoundland
- Fort William, St. John's, Newfoundland
- Fox, Terry, No plaque in place, recommended location -- St. John's, Newfoundland
- French Shore, Port au Choix, Newfoundland
- Gilbert, Sir Humphrey, St. John's, Newfoundland
- Government House, St. John's, Newfoundland
- Grenfell, Sir Wilfred, St. Anthony, Newfoundland
- Harbour Grace Court House, Harbour Grace, Newfoundland
- Harvey, Sir John, St. John's, Newfoundland
- Hawthorne Cottage, Brigus, Newfoundland
- Hebron Mission, Hebron, Labrador
- Hopedale Mission, Hopedale, Labrador
- Indian Point, Red Indian Lake, Newfoundland
- Joe, Sylvester, Conne River, Newfoundland
- Kirke, Sir David, Calvert , Newfoundland
- L'Anse Amour, L'Anse-Amour, Labrador
- L'Anse aux Meadows, St. Anthony, Newfoundland
- Landing of John Guy, Cupids, Newfoundland
- Landing of the Trans-Atlantic Submarine Cable, Heart's Content, Newfoundland
- Little, Philip Francis, No plaque in place, recommended location -- St. John's, Newfoundland
- Mallard Cottage, St. John's, Newfoundland
- Maritime Archaic Cemeteries/Phillips Garden Dorset, Port au Choix, Newfoundland
- Mitchell, Mattie, Gros Morne National Park of Canada, Newfoundland
- Murray Premises, St. John's, Newfoundland
- Newfoundland Outport Nursing and Industrial Association (NONIA), Pool's Cove, Fortune Bay, Newfoundland
- Newfoundland's Entry into Confederation, St. John's, Newfoundland
- Okak, Okak, Newfoundland and Labrador
- Port au Choix, Port au Choix, Newfoundland
- Port Union Historic District, Port Union, Newfoundland
- Pratt, E. J., Western Bay, Newfoundland
- Red Bay, Red Bay, Labrador
- Reeves, Chief Justice John, St. John's, Newfoundland
- Rennie's Mill Road Historic District, St. John's, Newfoundland
- Role of Placentia, Placentia, Newfoundland
- Ryan Premises, Bonavista, Newfoundland
- Shanawdithit, St. John's, Newfoundland
- Shea, Sir Ambrose, St. John's, Newfoundland
- Signal Hill, St. John's, Newfoundland
- Smallwood, Joseph 'Joey' Roberts, St. John's, Newfoundland
- Southcott, Mary Meager, St. John's, Newfoundland
- St. John the Baptist Anglican Cathedral, St. John's, Newfoundland
- St. John's Court House, St. John's, Newfoundland
- St. John's Ecclesiastical District, St. John's, Newfoundland
- St. John's Regatta, St. John's, Newfoundland
- St. John's WWII Coastal Defences, St. John's, Newfoundland
- St. Patrick's Roman Catholic Church, St. John's, Newfoundland
- St. Thomas Rectory / Commissariat House and Garden, St. John's, Newfoundland
- Tilting, Tilting, Newfoundland
- Torbay, Torbay, Newfoundland
- Transatlantic Flights, Harbour Grace, Newfoundland
- Wabana Iron Ore Mines, St. John's, Newfoundland
- Walled Landscape of Grates Cove, Grates Cove, Newfoundland
- Water Street Historic District, St. John's, Newfoundland
- Whitbourne, Sir Richard, Trinity, Newfoundland
- Winning of Responsible Government, St. John's, Newfoundland
- Winterholme, St. John's, Newfoundland
- Winterhousing, Deep Cove, Newfoundland and Labrador
